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Facts About the CIR

What is the CIR?

The Center for Immunization Research (CIR) is part of the Department of International Health of the Johns Hopkins University Bloomberg School of Public Health. The CIR was established in 1985 by Dr. Mary Lou Clements-Mann.  For more than 25 years, the CIR has provided leadership in the areas of early phase vaccine evaluation and vaccine education efforts. CIR investigators primarily conduct Phase I and II safety, immunogenicity, and efficacy trials of new vaccine candidates. The CIR is also the world leader in training other research professionals to develop the skills and infrastructure needed to design, conduct, and evaluate clinical vaccine trials, with a focus on applied Good Clinical Practice (GCP).

1.)    What types of studies are being done at the CIR?

Outpatient

Inpatient

2.)    What is the difference between inpatient and outpatient studies?

  • Inpatient studies require you to remain in a clinical research isolation facility for a specificied  time. Inpatient studies range from a few days to a few weeks. CIR iInpatient studies are conducted in an isolation facility on the Johns Hopkins Bayview Medical Center campus. 
  • Outpatient studies do not require an over-night stay at the clinic.  Volunteers come to the clinic to receive prcoedures that are described in the research protocol..

3.)    How can I participate in studies at the CIR?

For more information on currently enrolling studies at the CIR, click here.

4.)    Where  is the CIR located?

  • The CIR’s outpatient clinic is located at 624 N. Broadway, Hampton House, Suite 117, Baltimore, MD  21205.
  • The inpatient unit is located at Johns Hopkins Bayview Medical Center, 301 Mason Lord Drive, Suite 4300, Baltimore, MD 21224.

5.)    What is my role if I participant in a CIR clinical study?

If you choose to participate in a vaccine study conducted by the CIR you will first need to be screened to determine if you are eligible to participate. If you are eligible, you must be consented by one of the CIR staff members. You will then undergo a physical exam and you will be asked to give a blood sample for laboratory evaluation to determine if you are healthy to participate in a study. A urine sample may also be collected during the screening visit. Once you are enrolled in a study, you are responsible for the requirements of that study when you consent to participate. 

6.)    What is a screening and what happens at a screening? (hyper link to screening process)?

Screening is the process to determine if you are healthy enough to participate in a vaccine research study. The Screening is the initial step to participating in a vaccine clinical trial.

For more information about our screening process click here.

7.)    Will I be paid for screening?

No, you will not be paid for general screening in adult studies.

Please check our currently enrolling page for more information on study compensation.

8.)    What if I quality to participate in a study?

If you qualify to participate, you may be invited to enroll in a study. You will be asked to read our screening Informed Consent form. This consent form outlines the screening process. If you agree, you will be asked to sign and date the form, giving us permission to evaluate your general health. It is important to note that if at anytime during this visit, something is discovered that will exclude you from participating in a research study, you will be told. Once you have read the consent form, you will be asked to complete a no-fail comprehension quiz. This is to assure that you understand all the major points of the Informed Consent form, and to address any parts of the Informed Consent form that need clarification. This part of the screening process takes about 25-35 minutes to complete. 

9.)    Can I enroll in a study if I am pregnant or planning to be come pregnant?

No. If you are pregnant, planning to become pregnant or breastfeeding, you cannot participate in our studies.

Any women of childbearing age who wants to participate in CIR studies must agree to use an effective form of birth control for the duration of the study.

10.) What is a vaccine?

A vaccine is used in medicine to enhance or induce immunity to a particular disease. Please visit our resource page to learn more about the history of vaccines.click here

11.) What is a study participant?

A study participant is an individual who volunteers to enroll in a research clinical study. You can withdraw your participation at anytime without penalty or loss of any medical care that you would otherwise be entitled to receive.

12.) What happens if I am a a study alternate?

If you qualify to join a study, you may be asked to participate in a study in the event that another participant becomes unable to continue participation.

13.) What is a Study Sponsor?

Study Sponsors are individuals, groups or organizations that fund the research project. Clinical trials are sponsored or funded by a variety of organizations or individuals such as physicians, medical institutions, foundations, voluntary groups, and pharmaceutical companies,including federal agencies such as the National Institutes of Health (NIH), the Department of Defense (DOD), and the Department of Veteran's Affairs (VA).

14.) Who will see my information if I participate in a clinical trial?

  • Study personnel
  • Institutional Review Board (IRB)
  • Departmentof Health and Human Services (DHHS)

15.) Who do I talk to if I have questions about vaccine clincial trials at the CIR?

You may contact the Center for Immunization Research:

410-955-7283
toll free (877-863-1374)
Johns Hopkins Project SAVE
Center for Immunization Research
624 N. Broadway
Baltimore, MD 21205
Email: projectsave@jhsph.edu

For more information about our vaccine clinical trials please visit the CIR studies page or your may contact  

16.) Does the CIR participate in pediatric trials?

For information about pediatric vaccine clinical trials, please contract our office at 410-502-3333.

To learn more about participating in a vaccine clinical trial, visit our ENROLL now page or you may contact us at (410-955-7283) (toll free 877-863-1374).